Biochemical innovations and pioneering laboratory work.

Assoc-Prof Dr MA Natural Philosophy
Joachim Greilberger

Professional background

Studied chemistry from 1988 at the Karl-Franzens-University Graz

Worked from 1990 as a chemistry student at the Medical Biochemistry of the Medical Faculty of the Karl-Franzens University

1994 Master's degree for chemistry and Doctor of Chemistry (subject biochemistry with Prof. Dr. H. Esterbauer)

Scientific employee in the medical diagnostics laboratory Prof. Dr. Holasek and Prof. Dr. Petek, Körösistraße, Graz, Austria (1994 - 2005)

Degree in chemistry and medical biochemistry at the Karl-Franzens University in Graz

From 1999 to 2000 in 3 EU projects at the ETH Zurich (Prof Dr Bruno Ösch, student of Prof Dr Prusiner, Nobel Prize Winner) and IAH Edinburgh active in the development of chemiluminescence methods (CLIA and Westernblot; Prof Dr David Taylor, Dr Robert Sommerville) for the identification of an infectious prion unit from histoid homogenate, blood and plasma Cohn fractions from plasma

Development of the measurement method that makes the direct effects of damage caused by radicals (RONS) measurable

1999 - 2000: University assistant at the Institute for Medicinal Chemistry at the Medical Faculty of the Karl-Franzens University Graz

University lecturer for medicinal chemistry at the Institute for Medicinal Chemistry and Pregl Laboratory

Habilitation as Assoc Prof Dr MA at the Institute for Medicinal Chemistry at the Medical Faculty of the Karl-Franzens University Graz

From 2004 Assoc Prof MA at the Institute for Physiological Chemistry at Med Uni Graz

Currently working at the Chair of Physiological Chemistry, Otto Loewi Center of the Med Uni Graz as a researcher and lecturer (module coordination of the subject Physiological Chemistry for PMII, PM III, NAWI Track I and PT NAWI Track II pharmaceutical industry for the pharmaceutical company C.Y.L. GesmbH)

Founder and owner of the Institute for Laboratory Science Dr Greilberger - a special laboratory for oxidative stress (from 2007) under the Institute for Medical Diagnostics Labor Dr Thomas Petek, Körösistrasse, Graz, Austria

Biochemical innovations and pioneering laboratory work.

Univ.-Prof. Mag. Dr. rer. nat.
Joachim Greilberger

Professional background

Studied chemistry from 1988 at the Karl-Franzens-University Graz

Worked from 1990 as a chemistry student at the Medical Biochemistry of the Medical Faculty of the Karl-Franzens University

1994 Master degree for chemistry and doctor of chemistry (subject biochemistry with Prof. Dr. H. Esterbauer)

Scientific employee in the medical diagnostics laboratory Prof. Dr. Holasek and Prof. Dr. Petek, Körösistraße, Graz, Austria (1994 - 2005)

Degree in chemistry and medical biochemistry at the Karl-Franzens University in Graz

From 1999 to 2000 in 3 EU projects at the ETH Zurich (Prof. Dr. Bruno Ösch, student of Prof. Dr. Prusiner, Nobel Prize Winner) and IAH Edinburgh active in the development of chemiluminescence methods (CLIA and Westernblot; Prof. Dr. David Taylor, Dr. Robert Sommerville) for the identification of an infectious prion unit from histoid homogenate, blood and plasma Cohn fractions from plasma

Development of the measurement method that makes the direct effects of damage caused by radicals (RONS) measurable

1999 - 2000: University assistant at the Institute for Medicinal Chemistry at the Medical Faculty of the Karl-Franzens University Graz

University lecturer for medicinal chemistry at the Institute for Medicinal Chemistry and Pregl Laboratory

Habilitation as ao.Univ.-Prof. Mag. Dr. at the Institute for Medicinal Chemistry at the Medical Faculty of the Karl-Franzens University Graz

From 2004 ao.Univ.-Prof. Mag. Dr. at the Institute for Physiological Chemistry at Med Uni Graz

Currently working at the Chair of Physiological Chemistry, Otto Loewi Center of the Med Uni Graz as a researcher and lecturer (module coordination of the subject Physiological Chemistry for PMII, PM III, NAWI Track I and PT NAWI Track II pharmaceutical industry for the pharmaceutical company C.Y.L. GesmbH)

Founder and owner of the Institute for Laboratory Science Dr. Greilberger - a special laboratory for oxidative stress (from 2007) under the Institute for Medical Diagnostics Labor Dr. Thomas Petek, Körösistrasse, Graz, Austria

Focus areas

Research

After many years of intensive research, Prof Dr Greilberger and Prof Dr Herwig discovered the formula for the patented alphaH2+®, which protects against oxidative stress and positively favors the energy metabolism of the human organism.

The two founders of HG Pharma have been working on new biochemical forms of therapy for system regeneration for many years.

Confirmed by the 2019 Nobel Prize winners in the Physiology or Medicine category, cell researchers Kaelin, Ratcliffe and Semenza, who, among others, physiologically demonstrated the effects of oxidative stress on HIF-1 alpha.

Patents

Prof Dr Greilberger and Prof Dr Herwig are patent holders for several groundbreaking biomedical products, the effectiveness of which has been proven in numerous studies.

Furthermore, Prof Dr Greilberger patented the following research results and scientific achievements:

Selectively deglycosylated vitamin D binding protein (dgVDBP) and cholecalciferol (Calciol) and manufacturing process.

Antioxidant composition for histoid and organ preservation.

Use of alpha-ketoglutaric acid and 5-hydroxymethylfurfural to reduce oxidative stress.

Current publications

– an excerpt

Paulus S Rommer, Dietmar Fuchs, Friedrich Leblhuber, Rainer Schroth, Michaela Greilberger, Erwin Tafeit, Joachim Greilberger: Lowered Levels of Carbonyl Proteins after Vitamin B Supplementation in Patients with Mild Cognitive Impairment and Alzheimer's Disease. Neurodegener Dis. 2016; 16(3-4):284-289

Manfred Lamprecht, Simon Bogner, Kurt Steinbauer, Burkhard Schuetz, Joachim Greilberger, Bettina Leber, Bernhard Wagner, Erwin Zinser, Thomas Petek, Sandra Wallner-Liebmann, Tanja Oberwinkler, Norbert Bachl, Gert Schippinger: Effects of zeolite supplementation on parameters of intestinal barrier integrity, inflammation, redoxbiology and performance in aerobically trained subjects. J Int Soc Sports Nutr. 2015; 12(2):40-40

Veronika Matzi, Joachim Greilberger, Jörg Lindenmann, Nicole Neuboeck, Stephan Nuhsbaumer, Sieglinde Zelzer, Erwin Tafeit, Alfred Maier, Maria-Frey Smolle-Juettner: Application of Hyperbaric Oxygen Reduce Oxidative Damage of Plasmatic Carbonyl Proteins and 8-OHdG by Activating Glutathion Peroxidase. Clin Lab. 2015; 61(5-6):587-593

Paulus S Rommer, Joachim Greilberger, Sabine Salhofer-Polanyi, Eduard Auff, Fritz Leutmezer, Ralf Herwig: Elevated levels of carbonyl proteins in cerebrospinal fluid of patients with neurodegenerative diseases. Tohoku J Exp Med. 2014; 234(4):313-317

Joachim Greilberger, Michaela Greilberger, Radovan Djukic: Biomarkers Part I: Biomarkers to estimate bioefficacy of dietary/supplemental antioxidants in sport. Bocan Raton, Florida: Taylor & Francis Group; 2014. pp. 14.

Joachim Greilberger: Preclinical and clinical testing of a alpha-ketoglutarate/5-HMF/N-actyl-selenomethionine and N-acteyl-methionine for treating tumors. Journal of Cancer Science and Therapy. 2013; 5(10):76-76.-3rd; World Congress on Cancer Science & Therapy; OCT 21-23, 2013; San Francisco, USA. -Oral Communication

Manfred Lamprecht, Simon Bogner, Gert Schippinger, Kurt Steinbauer, Florian Fankhauser, Seth Hallstroem, Burkhard Schuetz, Joachim Greilberger: Probiotic supplementation affects markers of intestinal barrier, oxidation, and inflammation in trained men; a randomized, double-blinded, placebo-controlled trial. J Int Soc Sports Nutr. 2012; 9(1):45-45

Magdalena Hardt-Stremayr, Joachim Greilberger, Veronika Matzi, Jörg Lindemann, Alfred Maier, Reinhold Wintersteiger: Metabolism of 5-hydroxymethylfurfural following the application of a novel anti-cancer infusion solution. INT J CLIN PHARM. 2011; 33(2):332-333.

Joachim Greilberger, Dietmar Fuchs, Friedrich Leblhuber, Michaela Greilberger, Reinhold Wintersteiger, Erwin Tafeit: Carbonyl proteins as a clinical marker in Alzheimer's disease and its relation to tryptophan degradation and immune activation. Clin Lab. 2010; 56(9-10): 441-448.

Veronika Matzi, Jörg Lindenmann, Andreas Muench, Joachim Greilberger, Heinz Juan, Reinhard Wintersteiger, Alfred Maier, Freyja Maria Smolle-Juettner: impact of preoperative micronutrient supplementation in lung surgery. A prospective randomized trial of oral supplementation of combined alpha-ketoglutaric acid and 5-hydroxymethylfurfural. Eur J Cardiothorac Surg. 2007; 32(5): 776-782.

Joachim Greilberger, Karl Öttl, Gerhard Cvirn, Gilbert Reibnegger, Günther Jürgens: Modulation of LDL oxidation by 7,8-dihydroneopterin. FREE RADICAL RES. 2004; 38: 9-17.

Manfred Lamprecht, Joachim Greilberger, Karl Öttl: Analytical aspects of oxidatively modified substances in sports and exercises. NUTRITION. 2004; 20(7-8): 728-730.

Xiaosong Wang, Joachim Greilberger, Gerhard Ledinski, Gerd Kager, Beverly Paigen, Günther Jürgens: The hypolipidemic natural product Commiphora mukul and its component guggulsterone inhibit oxidative modification of LDL. ATHEROSCLEROSIS. 2004; 172: 239-246.

Joachim Greilberger, Xiaosong Wang, Gerhard Ledinski, Qi Chen, Günther Jürgens: Presence of aldehydic epitopes on a minor low-density lipoprotein fraction. Free Radic Biol Med. 1999; 26(11-12):1489-1494

Joachim Greilberger, Günther Jürgens: Oxidation of high-density lipoprotein HDL3 leads to exposure of apo-AI and apo-AII epitopes and to formation of aldehyde protein adducts, and influences binding of oxidized low-density lipoprotein to type I and type III collagen in vitro1. Biochem J. 1998; 331 ( Pt 1)(2):185-191

Sonja Koestenbauer, Philipp Stiegler, Vanessa Stadlbauer, Ursula Mayrhauser, Bettina Leber, Martin Schweiger, Andrae Wasler, Günther Prenner, Michael Sereinigg, Sieglinde Zelzer, Tatjana Stojakovic, Michael Scarpatetti, Antonia Griesbacher, Joachim Greilberger, Karlheinz Tscheliessnigg: Myeloperoxidase and carbonyl proteins: promising markers for non-invasive monitoring of graft rejection after heart transplantation. J Heart Lung Transplant. 2010; 29(12): 1352-1357.

Joachim Greilberger, Otto Schmut, Günther Jürgens: In vitro interactions of oxidatively modified LDL with type I, II, III, IV, and V collagen, laminin, fibronectin, and poly-D-lysine. Arterioscler Thromb Vasc Biol. 1997; 17(11):2721-2728

And many more

To the HG Pharma products

Innovative bio-pharmacology to activate and support the immune system and highly effective facial care to inhibit the aging process caused by skin metabolism.

Gain balanced health by boosting energy within body cells.

Natural dietary supplement for increased performance
and maximum regeneration.

The new immune-regulating therapy product boosts the body’s natural defenses.

ImmunoD® ATSM is the first medical dietary supplement worldwide for the treatment of autism diseases.

Stops the skin aging process effectively and gives you a youthful and fresh look and appearance.

MediSeptic protects against viruses and bacteria for up to 2 hours and 99,999 % (Log3).